David Klein Gallery was established in Birmingham, Michigan in 1990 with an exhibition program focused on presenting national and regional contemporary artists. Since its founding, the gallery has maintained a strong interest in Post War American and European art, presenting historical surveys by significant 20th Century artists including Alexander Calder, Richard Diebenkorn, Jean Dubuffet, Max Ernst, Alex Katz, and Bob Thompson. 
In 2015, a second gallery was opened in downtown Detroit on historic Washington Boulevard. The scale of this architecturally significant space allowed for an expansion of the gallery’s contemporary program to include large-scale exhibitions of paintings, sculpture, photography, and installations by emerging, mid-career, and established contemporary artists. Exhibited artists include Ebitenyefa Baralaye, Emmy Bright, Susan Goethel Campbell, Jack Craig, Iris Eichenberg, Kim McCarty, Benjamin Pritchard, Kelly Reemtsen, Robert Schefman, Rosalind Tallmadge, and Neha Vedpathak.
Throughout its thirty-four year history, David Klein Gallery has consistently cultivated a dialog between contemporary and historical artists. By working closely with the estates of Al Held, Clement Meadmore, Robert Motherwell, and Jack Tworkov, the gallery presents compelling and historically significant exhibitions to our Detroit audience. That practice, paired with a diverse program of exceptional contemporary artists, affirms its status as one of the leading galleries in the Mid-West. It is the only Detroit based member of the prestigious Art Dealers Association of America (ADAA).  In addition to the rigorous exhibition schedule in both Metro Detroit locations, David Klein Gallery partcipates annually in art fairs in New York, Chicago, Miami, and Los Angeles. 
David Klein Gallery has helped build notable collections with discerning collectors since its inception and maintains working relationships with numerous museums and curators. The gallery has placed work in multiple national institutions including the Detroit Institute of Arts, Cranbrook Art Museum, University of Michigan Museum of Art, Flint Institute of Arts, Williams College Museum of Art, and the International African American Museum.